Artificial intelligence tool for reading MRI scans could transform prostate cancer surgery and treatment

Researchers at the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University have preliminarily validated an artificial intelligence (AI) tool to predict how likely the disease is to recur following surgical treatment for prostate cancer. The tool, called RadClip, uses AI algorithms to examine a variety of data, from MRI scans […]

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Principles of care established for young adults with substance use disorders

A national group of pediatric addiction medicine experts have released newly-established principles of care for young adults with substance use disorder. Led by the Grayken Center for Addiction at Boston Medical Center, the collection of peer-reviewed papers was developed to guide providers on how to treat young adults with substance use disorder given their age-specific […]

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Researchers find NTRK fusions more common than expected in pediatric tumors

In a large study of pediatric cancer patients, researchers from Children’s Hospital of Philadelphia (CHOP) have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors. The researchers found that NTRK fusions are more common in […]

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IOF and IFCC review calls for harmonization of assays for reference bone turnover markers

Bone turnover markers (BTMs) in blood and urine are useful tools in monitoring osteoporosis treatment effects and may be useful for improving patient adherence. In 2011, a Joint Committee on Bone Metabolism of the International Osteoporosis Foundation (IOF) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) designated Procollagen type I N-propeptide (PINP) […]

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Revisiting the Global Workspace orchestrating the hierarchical organisation of the human brain

The celebrations in the 250th anniversary of the birth of Ludwig van Beethoven would not be the same without Herbert von Karajan’s brilliant performances conducting Beethoven’s memorable symphonies. The execution of any musical symphony is a hugely difficult task, demanding very significant skills on the part of each individual musician—but perhaps the most difficult task […]

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